Recent epidemiological reports of associations between socioeconomic status and epigenetic markers that predict vulnerability to diseases are bringing to light substantial biological effects of social inequalities. Here, we start the discussion of the moral consequences of these findings. We firstly highlight their explanatory importance in the context of the research program on the Developmental Origins of Health and Disease (DOHaD) and the social determinants of health. In the second section, we review some theories of the moral status of health inequalities. (...) Rather than a complete outline of the debate, we single out those theories that rest on the principle of equality of opportunity and analyze the consequences of DOHaD and epigenetics for these particular conceptions of justice. We argue that DOHaD and epigenetics reshape the conceptual distinction between natural and acquired traits on which these theories rely and might provide important policy tools to tackle unjust distributions of health. (shrink)

Most scientific theories are globally inconsistent. Chunk and Permeate is a method of rational reconstruction that can be used to separate, and identify, locally consistent chunks of reasoning or explanation. This then allows us to justify reasoning in a globally inconsistent theory. We extend chunk and permeate by adding a visually transparent way of guiding the individuation of chunks and deciding on what information permeates from one chunk to the next. The visual representation is in the form of bundle diagrams. (...) We then extend the bundle diagrams to include not only reasoning in the presence of inconsistent information or reasoning in the logical sense of deriving a conclusion from premises, but more generally reasoning in the sense of trying to understand a phenomenon in science. This extends the use of the bundle diagrams in terms of the base space and the fibres. We then apply this to a case in physics, that of understanding binding energies in the nucleus of an atom using together inconsistent models: the liquid drop model and the shell model. We draw some philosophical conclusions concerning scientific reasoning, paraconsistent reasoning, the role of logic in science and the unity of science. (shrink)

Recent evidence of intergenerational epigenetic programming of disease risk broadens the scope of public health preventive interventions to future generations, i.e. non existing people. Due to the transmission of epigenetic predispositions, lifestyles such as smoking or unhealthy diet might affect the health of populations across several generations. While public policy for the health of future generations can be justified through impersonal considerations, such as maximizing aggregate well-being, in this article we explore whether there are rights-based obligations supervening on intergenerational epigenetic (...) programming despite the non-identity argument, which challenges this rationale in case of policies that affect the number and identity of future people. We propose that rights based obligations grounded in the interests of non-existing people might fall upon existing people when generations overlap. In particular, if environmental exposure in F0 will affect the health of F2 through epigenetic programming, then F1 might face increased costs to address F2's condition in the future: this might generate obligations upon F0 from various distributive principles, such as the principle of equal opportunity for well being. (shrink)

Le concezione stoica dei predicati come effetti incorporei di cause -- La nozione stoica di lekton -- Lo sviluppo della nozione di lekton -- La nozione stoica di ptōsis.

Antecedentes. En el 2007 se legalizó el aborto en la Ciudad de México, acusando una elevada mortalidad materna por aborto.Objetivo. Analizar los datos generales de la mortalidad materna y por aborto en el país y en la capital.Metodología. Estudio retrospectivo, con datos obtenidos del INEGI. Cálculo de la razón de mortalidad materna general y por aborto. Análisis de correlación de Pearson y regresión lineal de los resultados. Análisis de tendencias de incremento y decremento anual. Desglose de muertes maternas.Resultado. Regresión lineal (...) sobre la RMM nacional (R² = 0.87) con tendencia a la baja; RMM por aborto nacional (R² = 0.49) con débil tendencia hacia la baja; RMM por aborto en la Ciudad de México (R² = 0.001) no muestra una tendencia hacia la baja.Conclusión. La despenalización del aborto en la Ciudad de México no mostró tener un impacto en la reducción de muertes maternas por aborto. El aborto provocado ocupa el 12° lugar de las muertes maternas en México. (shrink)

Le sujet de cette étude est la manière dont Plotin, dans une perspective qui reste essentiellement platonicienne, interprète la notion de noeîn dans Parménide, surtout à la lumière du bien connu Fr. 3 DK, sur l’identité de l’être et de la pensée, dont Plotin, avec Clément d'Alexandrie, est notre source. Cette interprétation est essentielle pour comprendre la nature et la fonction ontologique-métaphysique de l’hypostase plotinienne du Noûs. La conception parménidienne de noeîn est profondément remaniée par Plotin et intégrée dans une (...) perspective compatible avec l’ontologie platonicienne et la métaphysique néoplatonicienne. (shrink)

The review article reconstructs the reception of Gramsci's writings in Italy from the postwar-period to the present. Compared to the Italian debate that has given little attention to Gramsci's writings, except for in some periods such as the 1970s, Gramsci's fortune has continued to grow internationally. Recent Italian contributions, such as the book of Alberto Bugio, Grasmci storico, criticised in this review, remain indebted to an historicist approach that does not allow a use of Gramscian categories as an optic for (...) interpreting and enacting the transformation of the present. The analysis concentrates on concepts such as 'passive revolution', 'fascism', 'Taylorism' and 'bureaucracy'. (shrink)

El objeto de la presente investigación se coloca en el contexto caracterizado por la crisis económica global iniciada en 2008. La finalidad principal consiste en analizar el problema del condicionamiento financiero de las políticas sociales redistributivas y del trabajo en el ordenamiento de la Unión Europea: sus efectos en la justiciabilidad de los derechos sociales frente a la Corte de justicia de la Unión Europea y los fundamentos filosóficos de la metamorfosis producida.